A retrospective analysis of the etiological characteristics and infection risks of patients critically ill with multidrug-resistant bacteria in rehabilitation wards
10.3760/cma.j.issn.0254-1424.2024.03.003
- VernacularTitle:危重症康复病房多重耐药菌感染患者的病原学特征及危险因素分析
- Author:
Huaping PAN
1
;
Zhen WANG
;
Xiaojiao ZHANG
;
Jin GONG
;
Jianfeng ZHAO
;
Lizhi LIU
;
Jiamei LIU
;
Huiyue FENG
;
Fang LV
;
Hui FENG
Author Information
1. 南京医科大学附属江宁医院康复医学中心，南京 211103
- Keywords:
Critical care rehabilitation;
Intensive care units;
Multidrug-resistant bacteria;
Infection;
Retrospective analyses
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2024;46(3):205-209
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the microbiological and disease distribution characteristics of multidrug-resistant bacteria in patients hospitalized in a critical care rehabilitation ward, and to analyze the risk factors leading to multidrug-resistant bacterial infections.Methods:Microbiology screening data describing 679 patients admitted to a critical care rehabilitation ward were retrospectively analyzed to divide the subjects into a multidrug-resistant group (positive for multidrug-resistant bacterial infections, n=166) and a non-multidrug-resistant group (negative for multidrug-resistant bacterial infections, n=513). The risk factors were then analyzed using logistic regression. Results:Among 369 strains of multidrug-resistant bacteria observed, 329 were gram-negative bacteria (89.2%), mainly Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli. They were distributed in sputum (56.9%) and mid-epidemic urine (28.2%) specimens. Patients whose primary disease was hemorrhagic or ischemic cerebrovascular disease accounted for 40.96% and 23.49% of the multidrug-resistant bacterial infections, respectively. Logistic regression analysis showed that albumin level, dependence on mechanical ventilation, central venous cannulation, or an indwelling urinary catheter or cystostomy tube were significant independent predictors of such infections.Conclusion:The multidrug-resistant bacterial infections of patients admitted to the critically ill rehabilitation unit are mainly caused by gram-negative bacteria. Their occurrence is closely related to low albumin levels and mechanical ventilation, as well as to bearing an indwelling central venous catheter, a urinary catheter or a cystostomy catheter.
