Polycystic ovary syndrome and spontaneous preterm birth
10.3760/cma.j.cn113903-20230804-00080
- VernacularTitle:多囊卵巢综合征对自发性早产的影响
- Author:
Yumei WEI
1
;
Xinyue HAN
;
Huixia YANG
Author Information
1. 北京大学第一医院妇产科，北京 100034
- Keywords:
Polycystic ovary syndrome;
Preterm birth;
Anti-Mullerian hormone;
Hyperandrogenism;
Metformin
- From:
Chinese Journal of Perinatal Medicine
2023;26(12):1040-1044
- CountryChina
- Language:Chinese
-
Abstract:
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among reproductive-age women, characterized by obesity, insulin resistance, chronic low-grade inflammation, and hyperandrogenemia. Studies have revealed that women with PCOS may experience an increased risk of various adverse pregnancy outcomes, such as gestational diabetes, hypertensive disorders of pregnancy, miscarriages, and preterm births. Preterm birth is an important cause of adverse outcome among perinatal infants. However, due to the complexity of its pathogenesis, the current intervention treatment of preterm birth often yields unsatisfactory results. Recent studies have discovered that women with PCOS have a higher risk of preterm birth than those without, suggesting that PCOS is a risk factor for preterm birth. This article reviews the research progress of PCOS-related preterm birth to offer new insights into the prevention and treatment of preterm birth in women caused by PCOS.
