Research progress on models for studying preeclampsia
10.3760/cma.j.cn113903-20221126-00991
- VernacularTitle:子痫前期模型工具研究进展
- Author:
Yu LIU
1
;
Jingsi CHEN
;
Lili DU
;
Qingqing CHEN
;
Dunjin CHEN
Author Information
1. 广东省产科重大疾病重点实验室，广州 510150
- Keywords:
Pre-eclampsia;
Trophoblasts;
Organoids;
Models, animal
- From:
Chinese Journal of Perinatal Medicine
2023;26(9):782-786
- CountryChina
- Language:Chinese
-
Abstract:
Preeclampsia, a serious complication in pregnancy, is a "placental disease" in obstetrics. The growth and development of human and other mammalian embryos are closely related to the placenta. This review summarizes several models for studying preeclampsia including in vitro cell models, placental explants, organoid models, rodent models and primates models, contributing to a deeper understanding of placental development and related pregnancy disorders.
