Interpretation for "sepsis associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative Workgroup"
10.3760/cma.j.cn441217-20231102-01101
- VernacularTitle:《第28届急性疾病质量倡议工作组共识报告：脓毒症相关急性肾损伤》解读
- Author:
Caihong LIU
1
;
Koyner JAY
;
Yuliang ZHAO
;
Ping FU
Author Information
1. 四川大学华西医院肾脏内科 四川大学华西医院肾脏病研究所，成都 610041
- Keywords:
Sepsis;
Acute kidney injury;
Diagnosis;
Acute Disease Quality Initiative;
Expert consensus
- From:
Chinese Journal of Nephrology
2024;40(3):237-244
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis-associated acute kidney injury (SA-AKI) is defined as the presence of acute kidney injury (AKI) in the context of sepsis. In the setting of genetic susceptibility, sepsis can lead to SA-AKI through various mechanisms. Based on differences in pathophysiological mechanisms, SA-AKI is categorized into different "endotypes" and manifests as distinct "subtypes". The combination of biomarkers and predictive models has the potential to early identify high-risk AKI patients and elucidate SA-AKI "endotypes". Volume resuscitation and blood purification are optimized strategies for SA-AKI treatment. Furthermore, clinical research on SA-AKI in children is promising.
