A case of tubulointerstitial nephritis and uveitis syndrome complicated with Fanconi syndrome and literature review
10.3760/cma.j.cn441217-20230518-00521
- VernacularTitle:合并范科尼综合征的肾小管间质性肾炎-葡萄膜炎综合征1例并文献复习
- Author:
Ying XU
1
;
Xinyu ZHANG
;
Qinglian WANG
;
Junhui ZHEN
;
Xiang LIU
Author Information
1. 山东第一医科大学附属省立医院肾内科，济南 250021
- Keywords:
Nephritis, interstitial;
Uveitis;
Fanconi syndrome;
Tubulointerstitial nephritis and uveitis syndrome
- From:
Chinese Journal of Nephrology
2024;40(1):56-60
- CountryChina
- Language:Chinese
-
Abstract:
The clinical diagnosis of tubulointerstitial nephritis and uveitis (TINU) syndrome combined with Fanconi syndrome is relatively rare. The paper reports a 47-year-old female patient of TINU syndrome with hypokalemia, hypophosphatemia, hypouricemia and renal impairment as initial symptoms followed by uveitis. Serological tests showed that the patient also met the diagnostic criteria of Fanconi syndrome. Renal tissue pathology confirmed tubular interstitial injury, manifested as interstitial nephritis with acute tubular injury. Ophthalmic examination confirmed iritis in the right eye. After excluding other primary diseases, the patient was diagnosed as TINU syndrome with Fanconi syndrome. After glucocorticoid therapy, ocular symptoms, renal impairment and electrolyte disturbance were significantly improved.
