Peritoneal dialysis-related peritonitis and bacteremia caused by Fusarium verticillioides: a case report and literature review
10.3760/cma.j.cn441217-20230321-00329
- VernacularTitle:轮枝样镰刀菌致腹膜透析相关性腹膜炎及菌血症1例并文献复习
- Author:
Ye LIU
1
;
Fuyun SUN
Author Information
1. 沧州市中心医院肾内二科，沧州 061000
- Keywords:
Fusarium;
Fusariosis;
Peritonitis;
Peritoneal dialysis;
Fusarium verticillioides
- From:
Chinese Journal of Nephrology
2023;39(12):935-938
- CountryChina
- Language:Chinese
-
Abstract:
Fusarium is a kind of conditional pathogenic fungus. There are few reports of peritonitis caused by Fusarium at home and abroad. This paper reports a case of Fusariumverticillioides peritonitis complicated with bacteremia and reviews relevant literature. The patient was admitted to the hospital due to fever and abdominal pain. After peritonitis was diagnosed, the initial treatment was vancomycin plus ceftazidime kept in the abdominal cavity every night for 3 days, but the effect was not good. The antibiotic was upgraded to vancomycin plus meropenem for 2 days, but still, there was no effect. Subsequently, Fusarium was found after ascites fluid culture, and the treatment regimen was changed to voriconazole antifungal therapy and hemodialysis. However, the patient developed a dialysis catheter-related infection. After the infection was cured, the fever was still repeated, and the infection indexes did not improve. Further, the pathogenic microorganism of whole blood infection was detected by high-throughput gene detection, and it was clinically confirmed as Fusarium verticillioides. At last, the patient recovered and was discharged from the hospital after treatment with voriconazole combined with amphotericin B. Fusarium is highly pathogenic, and it is hoped to attract more attention of clinicians.
