A case of atypical hemolytic uremic syndrome complicated with IgA nephropathy in children and literature review
10.3760/cma.j.cn441217-20230105-00105
- VernacularTitle:儿童非典型溶血尿毒综合征合并IgA肾病1例并文献复习
- Author:
Jianjiang ZHANG
1
;
Yibo CHENG
;
Yingzi WANG
;
Guolan XING
Author Information
1. 郑州大学第一附属医院儿科，河南省儿童肾脏病临床诊疗中心，郑州 450000
- Keywords:
Atypical hemolytic uremic syndrome;
Glomerulonephritis, IgA;
Diagnosis, differential;
Therapeutics;
Child
- From:
Chinese Journal of Nephrology
2023;39(9):708-712
- CountryChina
- Language:Chinese
-
Abstract:
Atypical hemolytic uremic syndrome (aHUS) is characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia and acute kidney injury. IgA nephropathy (IgAN) is a common primary glomerular disease, while aHUS combined with IgAN is rare, and has been reported rarely in the past. This paper reported a case of children with aHUS combined with IgAN. In the acute stage, she was treated with plasma therapy and glucocorticoid. After remission, she was treated with glucocorticoid combined with immunosuppressants. During the follow-up period, aHUS did not recur, the renal function was normal, and urinary protein decreased to weakly positive.
