Current status and progress of new technologies in the diagnosis of tuberculous meningitis
10.3760/cma.j.cn113694-20240102-00002
- VernacularTitle:结核性脑膜炎诊断新技术的现状与进展
- Author:
Yicheng LI
1
;
Ting WANG
;
Wenmian HUANG
;
Guodong FENG
Author Information
1. 复旦大学附属中山医院神经内科，上海200032
- Keywords:
Central nervous system infection;
Tuberculosis, meningeal;
Diagnosis
- From:
Chinese Journal of Neurology
2024;57(3):302-308
- CountryChina
- Language:Chinese
-
Abstract:
Tuberculous meningitis is a central nervous system infectious disease caused by Mycobacterium tuberculosis. Its clinical manifestations are nonspecific, and effective pathogenic diagnostic methods are lacking, which often lead to delayed diagnosis and treatment, impacting the prognosis of patients. Therefore, early and rapid etiological diagnosis is crucial for the diagnosis and treatment of tuberculous meningitis. This article provides a review of novel detection technologies developed in recent years that can be used for the diagnosis of tuberculous meningitis, covering nucleic acid detection methods, metabolomics, and proteomics, and offering prospects for future development.
