Phenytoin induced chorea: a case report and literature review
10.3760/cma.j.cn113694-20230403-00246
- VernacularTitle:苯妥英导致的舞蹈病1例并文献复习
- Author:
Shuning DU
1
;
Yang LI
;
Xinyao LI
;
Yuling TIAN
;
Qiuyan WANG
Author Information
1. 山西医科大学第一医院神经内科,太原 030001
- Keywords:
Phenytoin;
Drug side effects;
Chorea
- From:
Chinese Journal of Neurology
2023;56(11):1290-1293
- CountryChina
- Language:Chinese
-
Abstract:
Chorea is a rare adverse effect of phenytoin and is common in children, with widely variable clinical presentations. This article reported a case of an elderly woman presented chorea without nystagmus, ataxia, dysarthria and other typical vestibular-cerebellar symptoms, who took compound theophylline and ephedrine contained phenytoin to treat asthma for 1 year. The serum phenytoin concentrations were at toxic levels and chorea disappeared within 3 days after discontinuation of the drug. The clinical features of previously reported cases of phenytoin-induced chorea were also summarized.