Research progress on the relationship between periodontitis and chronic obstructive pulmonary disease
10.3760/cma.j.cn114798-20231010-00223
- VernacularTitle:牙周炎与慢性阻塞性肺疾病相关性研究进展
- Author:
Yan MAO
1
;
Yingqiu HU
;
Aibing LI
;
Ming OUYANG
Author Information
1. 上海市普陀区中心医院口腔科，上海200333
- Keywords:
Periodontitis;
Pulmonary disease, chronic obstructive;
Inflammation;
Microbiota
- From:
Chinese Journal of General Practitioners
2023;22(12):1315-1319
- CountryChina
- Language:Chinese
-
Abstract:
Periodontitis is a chronic periodontal disease with a high incidence, and chronic obstructive pulmonary disease (COPD) is considered to be a chronic airway inflammatory disease. In recent years, many studies have observed that there is a potential relationship between periodontitis and COPD. The periodontal condition of patients with COPD is relatively poor, and the composition of their oral microbiome is different from that of healthy people. The inflammation “spillage”and hypoxia may induce the occurrence and development of periodontal disease. At the same time, the risk of COPD in periodontitis patients may be related to the inhalation of periodontal pathogens and inflammatory factors. Regular periodontal sequence therapy can reduce the risk of acute exacerbation of the disease to a certain extent. Since periodontitis and COPD are both chronic progressive diseases characterized by chronic inflammation and accompanied by proteolytic destruction of connective tissue, they may share a common pathophysiological process and may be intrinsically linked. This article reviews the latest research progress on the relationship between chronic periodontitis and COPD, and possible interaction mechanism, in order to provide insight for further study on the interaction between the two conditions.
