Progress in the diagnosis and treatment of drug-induced liver injury
10.3760/cma.j.cn114798-20230628-00670
- VernacularTitle:药物性肝损伤的诊治进展
- Author:
Dantong MA
1
;
Xuefei DUAN
Author Information
1. 首都医科大学附属北京地坛医院综合科，北京 100015
- Keywords:
Drug induced liver injury;
Diagnosis;
Treatment;
Research progress
- From:
Chinese Journal of General Practitioners
2023;22(11):1204-1209
- CountryChina
- Language:Chinese
-
Abstract:
Drug induced liver injury (DILI) refers to the liver injury caused by chemicals, biological products, traditional Chinese patent medicines and simple preparations and other drugs managed by prescription drugs or non prescription drugs, as well as Chinese medicinal materials, natural drugs, health products, dietary supplements and other products, or their metabolites and even their excipients, pollutants, impurities, etc. DILI is one of the most common Adverse drug reaction. In recent years, the incidence of DILI in China has increased year by year, posing a serious threat to the health of patients. The clinical manifestations of drug-induced liver injury are diverse, and the pathogenesis is complex, making diagnosis and prevention difficult. This article reviews the definition, epidemiology, clinical characteristics, and progress in diagnosis and treatment of DILI.
