Impact of colorectal cancer on skeletal muscle atrophy in patients with and without obesity
10.3760/cma.j.cn113855-20231230-00460
- VernacularTitle:结直肠癌对肥胖和非肥胖患者骨骼肌萎缩的影响
- Author:
Qianyi WAN
1
;
Rui ZHAO
;
Yi CHEN
;
Yinghan SONG
;
Xiaoting WU
Author Information
1. 四川大学华西医院普外科胃肠外科病房，成都 610041
- Keywords:
Obesity;
Colorectal neoplasms;
Sarcopenia
- From:
Chinese Journal of General Surgery
2024;39(3):188-191
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore whether the degree of skeletal muscle atrophy in obese individuals under the influence of colorectal cancer is more severe than that in non-obese individuals.Methods:The clinical data of patients who underwent radical resection of colorectal cancer in our department from Jul 2020 to Dec 2021 was collected. Sixty-four obese patients were included and 64 non-obese patients were matched according to propensity score. At the same time, 51 obese patients were collected from non-tumor patients and matched with 51 non-obese patients. The psoas muscle index (PMI) of included patients was analyzed and compared.Results:The PMI of patients with colorectal cancer was significantly lower than that of corresponding non-tumor patients, regardless of gender and body weight (both P<0.05). The PMI of obese patients with colorectal cancer was significantly lower than that of non-obese patients ( P<0.05). Conclusions:The impact of colorectal cancer on skeletal muscle atrophy in obese individuals is greater than that in normal weight individuals. Therefore, the skeletal muscle status of obese patients with colorectal cancer should be evaluated more comprehensively.
