Clinicopathologic features and surgical efficacy of retroperitoneal ganglioneuroma
10.3760/cma.j.cn113855-20230106-00011
- VernacularTitle:腹膜后节细胞神经瘤的临床病理特征及手术疗效分析
- Author:
Maosheng TANG
1
;
Mengmeng XIAO
;
Shibo LIU
;
Wenqing LIU
;
Haicheng GAO
;
Chenghua LUO
Author Information
1. 北京大学国际医院腹膜后肿瘤外科，北京102206
- Keywords:
Neuroma;
Retroperitoneal neoplasms;
Pathology, clinical
- From:
Chinese Journal of General Surgery
2023;38(12):884-888
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical diagnosis and treatment methods and curative effect of retroperitoneal ganglioneuromaMethods:The clinical data of 32 cases of retroperitoneal ganglioneuroma admitted to Peking University International Hospital from Apr 2015 to May 2022 were retrospectively analyzed, and their clinical characteristics, surgical efficacy and prognosis were discussed.Results:Of the 32 patients with retroperitoneal ganglioneuroma, 17 had no obvious clinical symptoms, 7 complained abdominal distension and pain, 6 had lower back pain, and 2 had abdominal mass. Tumors were located near the adrenal and renal regions in 18 cases, on both sides of the spine below the kidneys in 11 cases, and in the pelvis in 3 cases. tumors were single in 28 cases, multiple in 4 cases.Tumors were surrounded by major blood vessels in 12 cases. R 0 or R 1 resection was carried out in 27 cases, and palliative R 2 resection in 5 cases, combined organ resection in 6 cases, and piecemed resection in 8 cases. The maximum tumor diameter was (13.2±4.9)cm, the intraoperative blood loss was 500 (50-6 000 ml), and 6 cases suffered from major postoperative complications. Between patients with tumors encircling and encroaching major blood vessels or not, there were significant differences in age, intraoperative blood loss, R 2 resection rate, and pieceneal resection rate between the two groups ( t=2.44, P=0.021; Z=2.37, P=0.018; χ2=4.57, P=0.033; χ2=11.38, P=0.001). There was no recurrence in patients with R 0 or R 1 resection. Conclusions:The prognosis of complete resection of retroperitoneal ganglioneuroma is good .Major blood vessels encroachment of the tumor often leads to incomplente (R 2) resection.
