Clinical Characteristics and Prognostic Factors of Nasopharyngeal Cancer.
10.12701/yujm.2005.22.1.72
- Author:
Chang Hoon BAI
1
;
Young Jung SEO
;
Sang Baik YE
;
Young Ho CHOI
;
Yong Dae KIM
;
Si Youn SONG
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Yeungnam University, Daegu, Korea. ssykhs@med.yu.ac.kr
- Publication Type:Original Article
- Keywords:
Nasopharyngeal cancer
- MeSH:
Brain;
Female;
Humans;
Liver;
Lung;
Male;
Medical Records;
Nasopharyngeal Neoplasms*;
Neck;
Neoplasm Metastasis;
Neoplasm Staging;
Prognosis;
Rare Diseases;
Recurrence;
Retrospective Studies;
Spine;
Survival Rate
- From:Yeungnam University Journal of Medicine
2005;22(1):72-80
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Nasopharyngeal cancer is a rare disease with a relatively poor prognosis because it tends to be diagnosed at an advanced stage. The aim of this study was to establish the clinical characteristics of nasopharyngeal cancer. MATERIALS AND METHODS: The medical records of 54 patients with nasopharyngeal cancer from January 1993 to December 2002 were reviewed retrospectively. Forty one cases were male (75.9%) and thirteen were female (24.1%). The average age was of 46.9 (range 16 to 78 years) years. The majority of patients (79.6%) were diagnosed in the advanced stage. The most common complaints were a neck mass (55.5%) and the WHO type III (53.7%) was the most frequent histological type. RESULTS: The cumulative survival rate for a 5-year period was 46.5% and the T stage, N stage, pathologic type, and clinical stage were not significantly related to the survival rate. Sixteen of 54 (31.5%) cases presented with a distant metastasis of the bone, lung, brain, spine, and liver, and six cases (11.1%) presented with a locoregional recurrence. CONCLUSION: TNM staging is not appropriate for predicting survival rate of nasopharyngeal carcinoma patients. Therefore, a newer staging system, which includes new factors, is needed to predict the prognosis.
