Metabolic reconfiguration in vitiligo: progress and future
- VernacularTitle:白癜风代谢重塑：进展和未来
- Author:
Chunying LI
1
;
Jianru CHEN
;
Shuli LI
Author Information
- Keywords: Vitiligo; Melanocytes; Metabolic reconfiguration; Glucose metabolism; Lipid metabolism; Amino acid metabolism; Metabolism of gut microbiota
- From: Chinese Journal of Dermatology 2024;57(1):8-11
- CountryChina
- Language:Chinese
- Abstract: Based on the results of the latest basic research on vitiligo, this article elucidates the significance of reconfiguration of glucose metabolism, lipid metabolism, amino acid metabolism, and metabolism of gut microbiota in the pathogenesis of vitiligo, attempts to delineate a panoramic picture of metabolic reconfiguration in vitiligo, and discusses the importance of dialectically and uniformly grasping the crosstalk between multiple metabolic pathways, and of thinking about the mechanisms of action of multiple metabolic pathway reconfiguration in the occurrence of vitiligo in individuals from a holistic perspective in future basic studies, in order to promote the understanding of the vitiligo pathogenesis and explore potential treatment methods for vitiligo.
