Role of neurogenic inflammatory factors in the pathogenesis of vitiligo
- VernacularTitle:神经源性炎症因子在白癜风发病机制中的研究进展
- Author:
Haoyang WANG
1
;
Yidan WANG
;
Yan LU
Author Information
- Keywords: Vitiligo; Neuro secretory systems; Autoimmunity; Psychological and neurological factors
- From: Chinese Journal of Dermatology 2024;57(1):78-81
- CountryChina
- Language:Chinese
- Abstract: Vitiligo is an acquired depigmented disease, and neurological factors may play an important role in its pathogenesis. Neurogenic inflammatory factors released by sensory nerves that control the skin can directly or indirectly regulate functions of keratinocytes, melanocytes, Langerhans cells, dermal dendritic cells, mast cells, dermal microvascular endothelial cells and immune cells. This review summarizes roles of several relevant neurogenic inflammatory factors in the occurrence and development of vitiligo, including neuropeptide Y, calcitonin gene-related peptide, catecholamines and nerve growth factor, with a view to providing new ideas for clinical treatment of vitiligo.
