Long non-coding RNAs in benign and malignant proliferative skin diseases
- VernacularTitle:长链非编码RNA在皮肤良恶性增生性疾病中的研究进展
- Author:
Xiao YANG
1
;
Yanchao ZENG
;
Li HE
;
Wenjuan WU
Author Information
- Keywords: Skin neoplasms; Gene expression regulation; RNA, noncoding; Long non-coding RNA
- From: Chinese Journal of Dermatology 2023;56(11):1080-1084
- CountryChina
- Language:Chinese
- Abstract: Long non-coding RNAs (lncRNAs) are a group of non-coding RNAs with a length of over 200 nucleotides. Recently, studies have shown that lncRNAs can regulate gene expression at the epigenetic, transcriptional, and post-transcriptional levels, affect the proliferation, migration, and infiltration of tumor cells, and participate in the occurrence and development of benign and malignant proliferative skin diseases, such as keloids, hemangioma, squamous cell carcinoma and melanoma. This review summarizes roles of lncRNAs in the pathogenesis of benign and malignant proliferative skin diseases.
