Associations between m 6A RNA methylation and cutaneous melanoma
- VernacularTitle:m 6A RNA甲基化与皮肤黑素瘤相关性的研究进展
- Author:
Fangqi CHEN
1
;
Yan LIANG
;
Ting WU
;
Changzheng HUANG
Author Information
- Keywords: Melanoma; RNA methylation; m 6A
- From: Chinese Journal of Dermatology 2023;56(9):889-892
- CountryChina
- Language:Chinese
- Abstract: N 6-methyladenosine (m 6A) modification can regulate gene expression by influencing RNA stability, nuclear transport, translation efficiency, alternative splicing and degradation. Current studies have shown that m 6A modification is associated with multiple biological behaviors of melanoma, such as proliferation, metastasis and resistance to immunotherapy, but specific mechanisms still need further study. This review summarizes the regulation of m 6A RNA methylation, and its related biological behaviors and mechanisms of action in melanoma.
