Preliminary Study on Prognostic Factors of New-onset Diabetes Mellitus After Distal Pancreatectomy for Pancreatic Cystic Tumor
10.3969/j.issn.1009-6604.2024.03.005
- VernacularTitle:胰腺囊性肿瘤患者行胰体尾切除术后新发糖尿病预后因素的初步探讨
- Author:
Yuan LI
1
;
Li ZHANG
;
Jinglin LI
;
Dianrong XIU
;
Hangyan WANG
Author Information
1. 北京大学第三医院普通外科,北京 100191
- Keywords:
New-onset diabetes mellitus;
Pancreatic cystic tumor;
Distal pancreatectomy
- From:
Chinese Journal of Minimally Invasive Surgery
2024;24(3):184-189
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the prognostic factors of new-onset diabetes mellitus(NODM)in patients with pancreatic cystic tumor after distal pancreatectomy(DP).Methods Between January 2010 and December 2019,92 patients with cystic pancreatic tumors in our hospital underwent laparoscopic DP.According to the inclusion and exclusion criteria,a total of 74 cases were included and divided into NODM group or normal glucose metabolism group based on whether postoperative NODM occurred.A univariate analysis was used to evaluate the prognostic factors of laparoscopic DP for pancreatic cystic tumors.P<0.05 was considered statistically significant,OR>4 was considered as a potential prognostic factor of clinical significance for NODM.Results NODM was diagnosed in26 cases(35.1%),with a median diagnosis time of 9 months(range,3-56 months)after surgery.Univariate analysis showed that transecting pancreas in the neck(OR = 11.000,P = 0.000),BMI≥25.0(OR = 4.333,P = 0.007),and family history of diabetes mellitus(OR =5.000,P =0.004)were prognostic factors of postoperative NODM.Conclusions When performing DP for pancreatic cystic tumors,it is advisable to preserve as much pancreatic tissue as possible and avoid cutting off the pancreas in the neck.Precise postoperative strategy of glucose metabolism surveillance for patients with BMI≥25.0 and family history of diabetes mellitus should be promoted.
