Comparison of chemical components of Lonicera fragrantissima and Lonicera japonica based on LC-MS
10.3969/j.issn.1001-1528.2024.03.022
- VernacularTitle:基于液质联用技术比较郁香忍冬花蕾与金银花化学成分
- Author:
Ying JIN
1
;
Le-Wen XIONG
;
Gao-Bin PU
;
Fang ZHANG
;
Jia LI
;
Long-Fei ZHANG
;
Yong-Qing ZHANG
Author Information
1. 山东中医药大学,济南 长清 250300
- Keywords:
Lonicera fragrantissima Lindl.et Paxt.;
Lonicerae japonicae Flos.;
LC-MS;
multivariate statistical analysis
- From:
Chinese Traditional Patent Medicine
2024;46(3):850-859
- CountryChina
- Language:Chinese
-
Abstract:
AIM To compare the components difference between Lonicera fragrantissima Lindl.et Paxt.(LFL)and Lonicerae japonicae Flos(LJF),and to evaluate the medicinal value of LFL,so as to provide reference for the development and utilization of LFL and LJF.METHODS With 70%methanol as extraction solvent,the components were analyzed by UPLC-TOF-MS,and the contents of 20 components were determined by HPLC-QQQ-MS.The components difference was determined by multivariate statistical analysis.RESULTS A total of 52 components were identified in the buds of LFL and LJF.There were 4 different components in LJF,and the contents of 20 quantitative components were significantly different.The contents of isochlorogenic acid C,ferulic acid,luteolin and rutin in the buds of LFL were more than 2 times that of LJF,and the contents of marchanic acid and marchanin were 11.96 times and 37.23 times that of LJF respectively.Maganin,isochlorogenic acid A,maganic acid,rutin and dicomachanic acid are the key differentiating components of LFL and LJF.CONCLUSION The buds of LFL and LJF have similar species,but the content difference is obvious.The buds of LFL have important medicinal value,which need further development and utilization.
