Simultaneous GC-MS determination of sixteen pesticide residues and safety assessment for Lycii Fructus
10.3969/j.issn.1001-1528.2024.01.025
- VernacularTitle:GC-MS法同时测定枸杞中16种农药残留的含量及安全性评价
- Author:
Jia-Qi QIN
1
,
2
;
Qiang-Qiang QI
;
Ya-Jun ZHANG
;
Yan WANG
;
Si-Yuan ZHAO
;
De-Yan CAO
;
Mei-Lin ZHU
Author Information
1. 宁夏医科大学公共卫生与管理学院, 宁夏 银川 750004
2. 宁夏医科大学, 宁夏环境因素与慢性病控制重点实验室, 宁夏 银川 750004
- Keywords:
Lycii Fructus;
pesticide residues;
GC-MS;
risk assessment
- From:
Chinese Traditional Patent Medicine
2024;46(1):143-149
- CountryChina
- Language:Chinese
-
Abstract:
AIM To establish a GC-MS method for the simultaneous content determination of sixteen pesticide residues in Lycii Fructus and perform safety assessment.METHODS The analysis was performed on DB-5MS chromatographic column(30 m×0.25 mm,0.25 μm)subjected to the programmed heating,with splitless injection of 1.0 μL dissolved sample at a flowing rate of 1.0 mL/min.Other parameters were as follows:injection port temperature of 250℃,electron impact ionization(EI),electron energy of 70 eV;ion source temperature of 230℃,multi-reaction monitoring mode,and collision gas.of high-purity N2.Pesticide residues with relatively high dietary risk were analyzed and discussed with regard to residue levels,dietary intake risk,risk ranking and cumulative exposure assessment.RESULTS Sixteen pesticides showed good linear relationships within their own ranges(r≥0.994 4),whose average recoveries were 70%-114%,with the RSDs of less than 2%.The highest average cyfluthrin residue of 0.999 2 mg/kg in Lycii Fructus of production regions and the highest average cypermethrin residue of 0.088 4 mg/kg in Lycii Fructus commodities were both detected.In Lycii Fructus of production regions with chronic hazard index(HI)value of 0.012 9 and acute HI value of 0.065 5 and their commodities with chronic HI of 0.001 2 and acute HI of 0.005 4,the pesticide residue of cypermethrin was the leading cause of chronic and acute dietary risk,and additionally,pyridaben within maximum residue limit(MRL)was the only detectectable highly toxic pesticide among the other most concerning pestcides of deltamethrin,pyridaben,chlorpyrifos,dichlorvos and methidathion.CONCLUSION There exist pesticide residues within MRL values in some samples of Lycii Fructus and the use of cypermethrin should be well-controlled.
