Clinical effects of Feining Paidu Decoction combined with conventional treatment on patients with Mycoplasma pneumoniae lobar pneumonia
10.3969/j.issn.1001-1528.2024.01.019
- VernacularTitle:肺宁排毒汤联合常规治疗对肺炎支原体大叶性肺炎患者的临床疗效
- Author:
Guo-Cai GAO
1
;
Guo-Lan GE
;
Dan-Ping PAN
;
Qian-Qian LI
;
Xue HAN
Author Information
1. 郑州大学附属儿童医院中医科, 河南 郑州 450000
- Keywords:
Feining Paidu Decoction;
conventional treatment;
Mycoplasma pneumoniae lobar pneumonia
- From:
Chinese Traditional Patent Medicine
2024;46(1):112-116
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the clinical effects of Feining Paidu Decoction combined with conventional treatment on patients with Mycoplasma pneumoniae lobar pneumonia.METHODS Ninety patients were randomly assigned into control group(45 cases)for 2-week intervention of conventional treatment,and observation group(45 cases)for 2-week intervention of both Feining Paidu Decoction and conventional treatment.The changes in clinical effects,TCM syndrome scores,inflammatory indices(WBC,N,CRP,ESR,PCT),inflammatory cytokines(TNF-α,IL-6,IL-8),coagulation indices(PLT,TT,PT,APTT,Fib,D-D),pulmonary imaging intergal and incidence of adverse reactions were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P<0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,inflammatory indices,inflammatory cytokines,PLT,pulmonary imaging intergal(P<0.05),especially for the observation group(P<0.05);the observation group exhibited prolonged TT,PT,APTT(P<0.05),and decreased Fib,D-D(P<0.05),which were more obvious than those in the control group(P<0.05).No significant difference in incidence of adverse reactions was found between the two groups(P>0.05).CONCLUSION For the patients with Mycoplasma pneumoniae lobar pneumonia,Feining Paidu Decoction combined with conventional treatment can safely and effectively alleviate clinical symptoms,and improve inflammatory responses,coagulation functions.
