Secondary metabolites from symbiotic fungi Talaromyces amestolkiae of Syngnathus acus
10.3969/j.issn.1001-1528.2023.12.023
- VernacularTitle:尖海龙共附生真菌Talaromyces amestolkiae次生代谢产物的研究
- Author:
Li-Rong LEI
1
;
Meng-Ying JIN
;
Da-Le GUO
;
Yun DENG
Author Information
1. 成都中医药大学,四川 成都 611137
- Keywords:
Syngnathus acus Linnaeus;
symbiotic fungi;
Talaromyces amestolkiae;
secondary metabolites;
isolation and identification
- From:
Chinese Traditional Patent Medicine
2023;45(12):3994-3999
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the secondary metabolites from symbiotic fungi Talaromyces amestolkiae of Syngnathus acus Linnaeus.METHODS The methanol extract from Talaromyces amestolkiae fermentation was isolated and purified by silica gel,Sephadex LH-20,TLC and preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Ten compounds were isolated and identified as 2,4-bis(1,1-dimethylethyl)benzeneethanol(1),aspergillumarins A(2),peniciisocoumarins H(3),2-(2-hydroxypropyl)-5-methyl-7-hydroxychromone(4),6-demethylvermistatin(5),penicimarin B(6),penicimarin C(7),8-hydroxy-6-methoxy-3-methylisocoumarin(8),polygonolide(9),ganoderpurine(10).CONCLUSION Compound 1 is a new natural product.Compounds 3-5,8-10 are isolated from this fungi for the first time.
