Chemical constituents from Nelumbinis Stamen
10.3969/j.issn.1001-1528.2023.12.022
- VernacularTitle:莲须化学成分的研究
- Author:
Yue LI
1
;
Tao WU
Author Information
1. 上海中医药大学中药研究所,上海 201203
- Keywords:
Nelumbinis Stamen;
chemical constituents;
isolation and identification
- From:
Chinese Traditional Patent Medicine
2023;45(12):3987-3994
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the chemical constituents from Nelumbinis Stamen.METHODS The methanol extract from Nelumbinis Stamen was isolated and purified by silica gel,C8 reversed phase column,Sephadex LH-20,preparative TLC and preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Twenty-one compounds were isolated and identified as erythrodiol(1),erythordiol-3-acetate(2),2α-hydroxy-oleanolic acid(3),oleanolic acid(4),4-epi-hederagenin(5),4-epi-hederagenin methyl ester(6),28α-homo-β-amyrin acetate(7),betulinic acid(8),24-ketocholesterol(9),7β-hydroxy-sitosterol(10),7α-hydroxy-sitosterol(11),3β-hydroxy-stigmast-5-en-7-one(12),(3β,5α,6β,22E)-6-methoxyergosta-7,22-diene-3,5-diol(13),dankasterone A(14),demethylincisterol A3(15),β-sitostenone(16),β-sitosterol(17),quercetin(18),isorhamnetin(19),kaempferol(20),luteolin(21).CONCLUSION Compounds 2,4-15 are isolated from genus Nelumbo for the first time.Compound 16 is isolated from this plants for the first time.
