Chemical constituents from Solanum muricatum and their antioxidant activities
10.3969/j.issn.1001-1528.2023.12.020
- VernacularTitle:人参果化学成分及其抗氧化活性
- Author:
Cheng WANG
1
,
2
;
Yan-Ping WANG
;
Yi XIONG
;
Ping ZHU
;
Gao-Xiong RAO
Author Information
1. 云南中医药大学中药学院,云南 昆明 650500
2. 云南省高校药食同用资源养生产品工程研究中心,云南 昆明 650500
- Keywords:
Solanum muricatum Ait.;
chemical constituents;
isolation and identification;
antioxidant activities
- From:
Chinese Traditional Patent Medicine
2023;45(12):3972-3979
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the chemical constituents from Solanum muricatum Ait.and their antioxidant activities.METHODS The 85%ethanol extract from S.muricatum was isolated and purified by silica gel,MCI,Sephadex LH-20,RP-C18,TLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.Their antioxidant activities were evaluated by DPPH free radical scavenging activity screening technology.RESULTS Twenty-five compounds were isolated and identified as caffeic acid(1),5-hydroxymaltol(2),4-methoxy-4-oxobutanoic acid(3),nicotinic acid(4),daucosterol(5),α-spinosterol-3-O-β-D-glucopyranoside(6),susaroyside A(7),ferulic acid(8),p-coumaric acid(9),methyl caffeate(10),ethyl caffeate(11),4,4-dimethylheptanedioic acid(12),calycosin(13),trans-4,4'-dihydroxystilbene(14),24-methylenecycloartanol(15),oleic acid(16),ethyl oleate(17),β-sitosterol(18),citrostadienol(19),pentacosane(20),β-sitosterol palmitate(21),(E)-4-[5-(hydroxymethyl)furan-2-yl]but-3-en-2-one(22),5,5'-oxybis(5-methylene-2-furaldehyde)(23),(E)-4-(5-(methoxymethyl)furan-2-yl)but-3-en-2-one(24),1,5-bis(5-methoxymethyl)furan-2-yl-penta-1,4-dien-3-one(25).The antioxidant capacity of 85%ethanol extract from S.muricatum was stronger than that of water extract.In the 85%ethanol extract from S.muricatum,the antioxidant capacities of each polar segment were 30%methanol,methanol,60%methanol,and water in turn.CONCLUSION Compounds 1-7 and 9-25 are isolated from this plant for the first time.The extracts of S.muricatum with different solvents and different polar segments have certain antioxidant activities.
