Clinical analysis of adult oculomoclonus-myoclonus syndrome with vertigo
10.3760/cma.j.cn112138-20230129-00040
- VernacularTitle:伴眩晕的成人眼阵挛-肌阵挛综合征临床分析
- Author:
Ye LIN
1
;
Chenjing SUN
;
Chao WEI
;
Ying LIN
;
Mengyang LIU
;
Jiaqi LIU
;
Qiang SHI
Author Information
1. 解放军总医院第一医学中心神经内科,北京 100853
- Keywords:
Vertigo;
Ataxia;
Autoimmunity;
Opsoclonus-myoclonus syndrome
- From:
Chinese Journal of Internal Medicine
2023;62(11):1341-1345
- CountryChina
- Language:Chinese
-
Abstract:
The clinical manifestation, physical and laboratory examination, electrophysiological, and imaging data of 2 female adult OMS patients with vertigo were analyzed at the Department of Neurology of the First Medical Center of Chinese PLA General Hospital from February 2021 to March 2022. The treatment strategy and clinical outcome were followed up. The two female patients were aged 42 and 66 years. Anti-NMDA receptor antibody and anti-GABAB receptor antibody were detected in serological screening, respectively. The two patients met the diagnostic criteria for OMS, and one was screened for breast tumor. The clinical symptoms of the two patients were relieved after immunomodulation therapy. OMS is a group of rare clinical syndromes; its clinical evaluation process should be standardized and the etiology should be actively searched for.