Predictive value of aMAP risk score for early recurrence of small hepatocellular carcinoma after microwave ablation
10.3760/cma.j.cn112138-20221108-00835
- VernacularTitle:aMAP风险评分对小肝癌微波消融术后早期复发的预测价值
- Author:
Shuyu DONG
1
;
Shuyun DENG
;
Rong FAN
;
Jinzhang CHEN
;
Xiao CHENG
;
Xin HAO
;
Wencong DAI
Author Information
1. 南方医科大学南方医院肝病中心暨感染内科 器官衰竭国家重点实验室 广东省病毒性肝炎研究重点实验室，广东省肝脏疾病研究所，广州 510515
- Keywords:
aMAP score;
Neoplasm recurrence, local;
Liver neoplasms
- From:
Chinese Journal of Internal Medicine
2023;62(11):1329-1334
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the value of the aMAP risk score (age, male, albumin -bilirubin, and platelets) to predict early recurrence within one year after microwave ablation in patients with small hepatocellular carcinoma. Methods:This was a retrospective study that enrolled 142 patients diagnosed with hepatocellular carcinoma who were treated with microwave ablation in the Department of Hepatology Unit of Nanfang Hospital, Southern Medical University from July 2016 to July 2021. The cohort enrolled 121 male and 21 female patients, including 110 patients that were <60 years old. All the patients were followed-up after microwave ablation to evaluate residual tumor and recurrence of tumor by computed tomography or magnetic resonance imaging. The observation indices mainly included general data and imaging data of patients. Using the X-tile tools, patients were divided into two groups: a high aMAP score group and a low aMAP score group. Multivariate Cox regression analysis was conducted for comparison of independent risk factors.Results:Multivariate Cox regression showed that high aMAP score, maximum tumor diameter >20 mm, and high AFP were the independent risk factors of early recurrence (all P<0.05). Kaplan-Meier survival curves showed that the median recurrence-free survival was 25.5 months in the low aMAP score group and 6.1 months in the high aMAP score group ( P=0.001). Conclusions:The aMAP score could predict the early recurrence within 1 year of small hepatocellular carcinoma after microwave ablation. Patients with high aMAP score should undergo rigorous postoperative follow-up evaluations..
