Glucocorticoid hypersensitivity syndrome: A case report and review of literature

VernacularTitle:糖皮质激素过度敏感综合征病例报道一例并文献复习
Author: Xiaozhen YE ¹ ; Yixin XU ; Xinyi YANG ; Yanyan WANG ; Jiaqing SHAO
Author Information

1. 中国人民解放军东部战区总医院内分泌科，南京　210002
Keywords: Glucocorticoid hypersensitivity; Cushing syndrome; Low cortisol levels; Mifepristone
From: Chinese Journal of Endocrinology and Metabolism 2024;40(1):64-67
CountryChina
Language:Chinese
Abstract: This article reports a patient with typical Cushing syndrome′s manifestations and extremely low plasma cortisol level, indicating glucocorticoid hypersensitivity syndrome. After treatment with the glucocorticoid receptor antagonist mifepristone, the patient′s Cushing symptoms were significantly relieved, and cortisol levels returned to normal. The aim of this report is to enhance clinical awareness among physicians regarding glucocorticoid hypersensitivity syndrome.