A case of testosterone-secreting adrenal tumor misdiagnosed as polycystic ovary syndrome
10.3760/cma.j.cn311282-20220422-00250
- VernacularTitle:一例分泌睾酮的肾上腺肿瘤误诊为多囊卵巢综合征
- Author:
Ping XU
1
;
Xiuzhen ZHANG
;
Qian YUAN
;
Jintao HU
;
Yan WU
Author Information
1. 深圳市人民医院（暨南大学第二临床医学院，南方科技大学第一附属医院）内分泌科 518020
- Keywords:
Hyperandrogenism;
Adrenal gland;
Oncocytoma;
Polycystic ovary syndrome
- From:
Chinese Journal of Endocrinology and Metabolism
2023;39(10):894-898
- CountryChina
- Language:Chinese
-
Abstract:
This article reports a case of adrenal tumor in a reproductive-aged woman with hyperandrogenism misdiagnosed as polycystic ovary syndrome. The patient presented with menstrual disorder, elevated testosterone levels, and polycystic ovaries, initially diagnosed as polycystic ovary syndrome. Menstrual regularity was achieved after intermittent use of ethinylestradiol/cyproterone acetate and progesterone. Five years later, during a physical examination, a mass was discovered in the right adrenal gland, accompanied by elevated testosterone levels, polycystic ovaries, obesity, and insulin resistance. Laparoscopic resection of the right adrenal tumor was performed, and the pathological diagnosis was adrenal cortical oncocytoma. Postoperatively, menstrual regularity was restored, and testosterone levels normalized. This case highlights the importance of considering adrenal tumors secreting androgens in patients clinically diagnosed with polycystic ovary syndrome, and emphasizes the need for regular adrenal imaging follow-up.
