Drug hypersensitivity syndrome induced by propylthiouracil: One case report and literature review
10.3760/cma.j.cn311282-20220425-00261
- VernacularTitle:丙硫氧嘧啶致药物超敏反应综合征一例并文献复习
- Author:
Qingyao WANG
1
;
Xinxin CHEN
;
Qiong SHEN
;
Huanhuan ZANG
;
Xiangguo CONG
;
Ling YU
;
Lei CHEN
Author Information
1. 南京医科大学附属苏州医院内分泌科，苏州 215002
- Keywords:
Autoimmune thyroiditis;
Propylthiouracil;
Drug-induced hypersensitivity syndrome;
Drug reaction with eosinophilia and systemic symptoms;
Adalimumab
- From:
Chinese Journal of Endocrinology and Metabolism
2023;39(9):804-808
- CountryChina
- Language:Chinese
-
Abstract:
This article reports a case of a 38-year-old female who developed drug hypersensitivity syndrome one month after receiving propylthiouracil. The patient showed improvement with adalimumab, corticosteroids, intravenous immunoglobulin, and plasma exchange. Propylthiouracil is a rare medication associated with drug hypersensitivity syndrome. Additionally, during the follow-up after discharge, rapid changes in thyroid autoantibodies and thyroid function were observed in this patient. By analyzing the progression of this case and reviewing literature, it aims to enhance clinical understanding and management.
