Effect of patent foramen ovale on development of post-operative stroke in patients undergoing non-cardiac surgery: a meta-analysis
10.3760/cma.j.cn131073.20231102.00308
- VernacularTitle:卵圆孔未闭对非心脏手术患者术后脑卒中发生的影响：meta分析
- Author:
Chen CHEN
1
;
Xiaoli YANG
;
Xiaotian SUN
;
Yunzhi SHEN
;
Huiwen JIANG
;
Yanhua YIN
Author Information
1. 复旦大学附属华山医院心外科，上海 200040
- Keywords:
Foramen ovale, patent;
Postoperative complications;
Stroke;
Meta-analysis;
Non-cardiac surgery
- From:
Chinese Journal of Anesthesiology
2024;44(3):292-296
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effect of patent foramen ovale on the development of post-operative stroke in the patients undergoing non-cardiac surgery using a meta-analysis approach.Methods:A comprehensive search was conducted across multiple databases including PubMed, Embase, Web of Science, CINAHL, Cochrane Library, China Biomedical Literature Database, Wanfang Data Knowledge Service Platform, and China Journal Full Text Database.The inclusion criteria encompassed studies assessing the correlation between patent foramen ovale and post-operative stroke.The primary outcome measure focused on the incidence of post-operative stroke, and secondary outcome measures comprised mortality, myocardial infarction rate, and readmission rate within 30 days after surgery. The quality of literature meeting the inclusion criteria was evaluated and data were extracted, and then meta-analysis was conducted using RevMan 5.4 software.Results:Eight retrospective cohort studies involving 21 142 237 patients were included.The results of meta-analysis showed that patent foramen ovale was associated with post-operative stroke and readmission within 30 days after surgery.There were no significant differences in all-cause mortality and myocardial infarction rates between patent foramen ovale group and mon-patent foramen ovale group ( P>0.05). Conclusions:Patent foramen ovale can increase the risk of post-operative stroke in the patients undergoing non-cardiac surgery.
