Anesthesia management of children undergoing resection of pheochromocytoma and paraganglioma
10.3760/cma.j.cn131073.20231024.00217
- VernacularTitle:儿童嗜铬细胞瘤和副神经节瘤切除术的麻醉管理
- Author:
Zenghua XU
1
;
Jianmin ZHANG
;
Nan ZOU
;
Tiehua ZHENG
;
Lianghong HUO
;
Lijing LI
;
Fang WANG
Author Information
1. 国家儿童医学中心 首都医科大学附属北京儿童医院麻醉科,北京 100045
- Keywords:
Pheochromocytoma;
Paraganglioma;
Child;
Anesthesia
- From:
Chinese Journal of Anesthesiology
2024;44(2):209-213
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To retrospectively analyze the anesthetic management characteristics of children undergoing resection of pheochromocytoma and paraganglioma (PPGL).Methods:The clinical data from patients undergoing resection of PPGL and confirmed histologically from January 1, 2010 to June 30, 2023 were retrospectively collected. The baseline characteristics, intraoperative conditions and postoperative complications were recorded.Results:The clinical data from 47 pediatric patients were analyzed. The overall incidence of hemodynamic instability events was 68% (32 cases). Lowering preoperative blood pressure to normal levels and the maximum diameter of tumor≥6 cm was helpful in reducing the incidence of the intraoperative hemodynamic instability events ( P<0.05). Postoperative hypotension developed in 7 cases, acute left heart failure in 1 case, arrhythmia in 1 case, adrenocortical insufficiency in 4 cases, and pulmonary infection in 13 cases. Conclusions:Thorough preoperative preparation, evidence-based anesthetic management, and meticulous postoperative vital sign monitoring can increase the perioperative safety for children undergoing resection of PPGL, thereby reducing the incidence of complications.