Relationship between preoperative pain threshold and chronic postsurgical pain in patients undergoing thoracoscopic pneumonectomy
10.3760/cma.j.cn131073.20230510.00903
- VernacularTitle:术前痛阈与胸腔镜肺切除术患者术后慢性疼痛的关系
- Author:
Yihao ZHU
1
;
Tao ZHU
;
Xuechao HAO
;
Fei WANG
Author Information
1. 四川省肿瘤医院·研究所 电子科技大学附属肿瘤医院麻醉科，成都 610041
- Keywords:
Pain threshold;
Preoperative period;
Chronic pain;
Postoperative complications;
Pneumonectomy;
Thoracoscopy
- From:
Chinese Journal of Anesthesiology
2023;43(9):1037-1041
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the relationship between preoperative pain threshold and chronic postsurgical pain (CPSP) in the patients undergoing thoracoscopic pneumonectomy.Methods:One hundred patients of both sexes, aged 18-75 yr, with body mass index of 18-35 kg/m 2, of American Society of Anesthesiologists Physical Status classification Ⅰ or Ⅱ, scheduled for thoracoscopic pneumonectomy at West China Hospital of Sichuan University from December 2019 to February 2020, were selected. The pain threshold was measured using Pain Vision at 1 day before surgery. Telephone follow-up was implemented by a pain questionnaire to assess CPSP (numerical rating scale score ≥1) at 3 months after surgery. Multivariate logistic regression was used to identify the risk factors for CPSP, and the receiver operating characteristic curve was used to evaluate the accuracy of preoperative pain threshold in predicting CPSP. Results:Ninety-four patients were finally enrolled, of which 38 cases (40%) developed CPSP. The results of multivariate logistic regression analysis showed that low preoperative pain threshold was an independent risk factor for CPSP ( OR=0.899, 95% confidence interval 0.854-0.946, P<0.001). The area under the receiver operating characteristic curve was 0.882 (95% confidence interval 0.804-0.960), Youden Index was 0.673, the sensitivity was 0.816, and the specificity was 0.857. Conclusions:Low preoperative pain threshold is an independent risk factor for CPSP, and preoperative pain threshold can predict the occurrence of CPSP in the patients undergoing thoracoscopic pneumonectomy.
