A case of recurrent renal pelvic sarcomatoid carcinoma treated with PD-1 inhibitor achieved complete remission

VernacularTitle:肾盂肉瘤样癌术后复发应用PD-1抑制剂治疗获完全缓解1例报告
Author: Lei GAO ¹ ; Chao LU ; Xiaokai SHI ; Yangyang SUN ; Xiaoli ZHOU ; Xiaopeng WU ; Lifeng ZHANG ; Li ZUO
Author Information

1. 南京医科大学附属常州市第二人民医院泌尿外科，常州　213000
Keywords: Kidney pelvis; Sarcomatoid carcinoma; Recurrence; Immunotherapy; Prognosis
From: Chinese Journal of Urology 2024;45(1):55-56
CountryChina
Language:Chinese
Abstract: Sarcomatoid carcinoma of the renal pelvis accounts for a very low percentage of malignant tumors in the renal pelvis and has a poor prognosis. This article reported a patient with sarcomatoid carcinoma of the renal pelvis. The patient presented with macroscopic hematuria as the first symptom, and CT suggested left renal occupancy, unilateral nephrectomy was performed, and pathology suggested sarcomatoid carcinoma of the renal pelvis. Three weeks after surgery, a follow-up CT showed tumor recurrence. Programmed death 1(PD-1)inhibitor was given once every 3 weeks. Repeated CT examination after 24 weeks of continuous treatment suggested that the recurrent tumor disappeared. The patients was followed-up for 42 months without tumor recurrence or metastasis.