IgG4-related disease with renal pelvic involvement suspiciously diagnosed as renal pelvis cancer: a case report

VernacularTitle:IgG4相关性疾病累及肾盂疑诊肾盂癌1例报告
Author: Song XU ¹ ; Lin ZHANG ; Tongzu LIU
Author Information

1. 武汉大学中南医院泌尿外科，武汉　430071
Keywords: IgG4-related disease; Renal pelvis cancer; IgG4-related kidney disease
From: Chinese Journal of Urology 2023;44(10):785-786
CountryChina
Language:Chinese
Abstract: Here we report a case of IgG4-related disease (IgG4-RD) involving the renal pelvis. A left renal pelvic mass was found on a patient during medical examination. The imaging examinations of CT urography, MRI and PET-CT all suggested renal pelvic cancer with multiple lymph node metastasis. The CT-guided biopsy of left renal pelvis was performed. Combining the pathological results and the serum IgG4 level, the IgG4-RD was finally clinically diagnosed. After oral methylprednisolone treatment, the volume of renal pelvic lesion reduced and the level of IgG4 decreased. IgG4-RD is a newly recognized fibro-inflammatory condition which may affect multiple organs. It is easy to be misdiagnosed as renal pelvis cancer when the renal pelvis is involved. Combing the tendency of multiple organ involvement, the serological test, the imaging features and the pathological characteristics, the correct diagnosis can be made. This disease responds well to glucocorticoid treatment, but the relapse is common.