Study on the association of poor oral health plus cognitive impairment with mortality risk in elderly people
10.3760/cma.j.issn.0254-9026.2023.11.006
- VernacularTitle:口腔健康不良和认知障碍与老年人死亡风险关系的研究
- Author:
Junle FAN
1
;
Chenxi LI
;
Jialin SUN
;
Tuerdi MAIMAITITUXUN
Author Information
1. 新疆医科大学第一附属医院(附属口腔医院)颌面创伤正颌外科，乌鲁木齐 830054
- Keywords:
Dental caries;
Periodontitis;
Edentulism;
Cognitive disorders;
Mortality
- From:
Chinese Journal of Geriatrics
2023;42(11):1301-1307
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the association of cognitive impairment plus poor oral health with mortality risk in older adults.Methods:This retrospective study included 3, 706 community-dwelling older adults enrolled in the National Health and Nutrition Examination Survey between January to June 2022, of whom 1, 973 were diagnosed with cognitive impairment and poor oral health.Based on cognitive performance and oral health status, 597 were categorized as having normal cognition and normal oral health, 506 as having normal cognition and poor oral health, 149 as having cognitive impairment and normal oral health and 226 as having cognitive impairment and poor oral health.The Cox proportional hazards regression model was used to test the effects of dental caries/periodontitis or edentulism and cognitive impairment on all-cause mortality and cardiometabolic mortality after adjusting for potential confounders.Results:During a median follow-up period of 13.4 years, 978(49.6%)patients died, with 264(13.5%)of cardiometabolic diseases). Cognitive impairment, periodontitis and tooth loss were all significant predictors of all-cause mortality.However, dental caries was not correlated with mortality.When these predictors were analyzed jointly, cognitive impairment and periodontitis were associated with an 83.1% increased risk of all-cause mortality and an 87.7% increased risk of cardiometabolic mortality compared with the healthy control group.The risk of all-cause mortality was highest in the presence of both cognitive impairment and tooth loss( HR=1.701, 95% CI: 1.338-2.161). Conclusions:In middle-aged and older individuals, the concomitant presence of cognitive impairment and periodontitis or edentulism may be associated with increased mortality.
