Analysis of the therapeutic effects of segmental resection and lobectomy for the elderly patients with non-small cell lung cancer
10.3760/cma.j.issn.0254-9026.2023.08.008
- VernacularTitle:老年人非小细胞肺癌肺段切除与肺叶切除的手术的治疗效果分析
- Author:
Wentong ZHANG
1
;
Ruidong MA
Author Information
1. 邛崃市医疗中心医院心胸外科，四川 邛崃 611530
- Keywords:
Thoracoscopy;
Pneumonectomg;
Carcinoma, non-small cell lung
- From:
Chinese Journal of Geriatrics
2023;42(8):932-935
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the efficacies of thoracoscopic segmentectomy and lobectomy in the treatment of elderly non-small cell lung cancer.Methods:260 elderly patients with non-small cell lung cancer(NSCLC)aged>65 years were randomly divided into a control group and a study group, with 130 in each group.The control group received lobectomy via the thoracoscope, while the study group received segmentectomy via the thoracoscope.Data from parameters for surgical performance of the two groups were analyzed and compared.The forced expiratory volume in one second(FEV1)and forced vital capacity(FVC)before and after surgery were compared between the two groups.Results:There was no significant difference between patients in the study group and the control group in the volume of intraoperative bleeding, the number of lymph node resection and the postoperative VAS score(all P>0.05). The operative time of the study group was(136.5±34.9)min, clearly longer than that of the control group(120.8±30.2)min, and the difference between the groups was significant( t=3.876, P<0.001), and the drainage time and total hospital stay for patients in the study group were(4.2±0.5)d and(7.2±1.6)d, respectively, which were much shorter than those for the control group(4.9±0.8)d and(8.7±2.1)d, respectively, and the differences between the groups were significant( t=8.445 and 6.421, P<0.001 for both). For the control group, the preoperative FEV1 and FVC were(99.25±7.15)% and(99.60±7.54)%, respectively, and the postoperative FEV1 and FVC were(65.08±13.06)% and(68.64±13.04)%, respectively; for the study group, the preoperative FEV1 and FVC were(98.42±8.99)% and(100.50±7.35)%, respectively, and the postoperative FEV1 and FVC were(85.09±10.04)% and(86.79±15.88)%, respectively.For both groups, the FEV1 and FVC levels after surgery were significantly lower than those before surgery( P<0.05), but the FEV1 and FVC levels in the study group were significantly higher than those in the control group( t=13.850 and 24.268, P<0.001 for both). There was no significant difference in the incidence of complications between the two groups( P>0.05). Conclusions:Compared with thoracoscopic lobectomy, thoracoscopic segmentectomy is more helpful to reduce postoperative drainage time and hospitalization time for elderly patients with non-small cell lung cancer, and can better protect patients' lung function.
