Influence of Escherichia coli in the intestine on short-term prognosis in patients with acute ischemic stroke:a primary study
10.3969/j.issn.1009-0126.2024.03.017
- VernacularTitle:肠道大肠杆菌对老年急性缺血性脑卒中患者短期预后影响的初步研究
- Author:
Ting WANG
1
;
Xiu'e WEI
;
Haiyan LIU
Author Information
1. 221000 徐州医科大学第二附属医院神经内科
- Keywords:
stroke;
Escherichia coli;
feces;
forecasting;
risk factors;
prognosis;
logistic models
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(3):309-312
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the content of intestinal Escherichia coli(E.coli)in patients with acute ischemic stroke(AIS)and to analyze the relationship between the bacteria and short-term prognosis of patients with cerebral stroke.Methods A total of 75 elderly AIS patients admitted to our department from March to December 2022 were enrolled,and divided into good prognosis group(47 cases)and poor prognosis group(28 cases)according to the results of modified Rankin scale 3 months after discharge.Multivariate logistic regression analysis was used to analyze the factors affecting the prognosis of the patients,and ROC curve analysis was employed to analyze the predictive value of the intestinal bacterial content for the short-term prognosis of stroke pa-tients.Results The NIHSS score at admission and E.coli content were significantly higher in the poor prognosis group than the good prognosis group(P＜0.01).Multivariate logistic regression analysis showed that NIHSS score at admission(OR=1.302,95％CI:1.077-1.573,P=0.006)and E.coli content(OR=2.803,95％CI:1.454-5.404,P=0.002)were independent risk factors for short-term poor prognosis in the AIS patients.ROC curve analysis indicated that the AUC value was 0.758 for E.coli content,0.718 for NIHSS score,and 0.818 when the 2 indicators combined together.Conclusion Intestinal E.coli content and NIHSS score may be related to the poor prog-nosis of elderly AIS patients.The higher the content of E.coli is,the worse the recovery of neuro-logical function,which affects the short-term prognosis of the patients.
