Diagnostic value of superb microvascular imaging and CTA combined with serum sdLDL-C for hypertension patients with ACI
10.3969/j.issn.1009-0126.2024.02.017
- VernacularTitle:微血管成像及CT血管造影联合小而密低密度脂蛋白胆固醇对高血压伴急性脑梗死的诊断价值
- Author:
Weihua XU
1
;
Yufang JI
;
Zhaoyang LU
;
Min XU
Author Information
1. 215000 苏州市第九人民医院超声科
- Keywords:
computed tomography angiography;
small and dense low-density lipoprotein cholester-ol;
superb microvascular imaging;
magnetic resonance angiography
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(2):188-191
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of superb microvascular imaging(SMI)grading,CT angiography(CTA),and serum small and dense low-density lipoprotein cholesterol(sdLDL-C)in elderly hypertension patients with acute cerebral infarction(ACI).Methods A ret-rospective study was conducted on 180 elderly hypertension patients admitted to our hospital from June 2021 to June 2023,and those admitted due to ACI were assigned into ACI group(95 cases)and those without into non-ACI group(85 cases).The SMI grade,CTA,and serum sdLDL-C level were compared between the two groups.ROC curve was plotted to analyze the diagnostic value of SMI grading and CTA combined with serum sdLDL-C for ACI in patients with hyperten-sion.Multivariate logistic regression analysis was employed to analyze the factors affecting the oc-currence of ACI in the patients.Results The ACI group had significantly larger proportion of hy-perlipidemia,and higher DBP,SBP,and HDL-C,and LDL-C than the non-ACI group(P<0.05).The proportion of SMI grade 2 and grade 3 and serum sdLDL-C level were also greatly higher[35.79%vs 10.59%,43.16%vs 8.24%,(1.62±0.25)mmol/L vs(1.35±0.19)mmol/L,P<0.01],and the proportion of SMI grade 0 and grade 1 was lower(11.58%vs 51.76%,9.47%vs 29.41%,P<0.01)in the ACI group than the non-ACI group.ROC curve analysis showed that the AUC value of SMI grade and CTA combined with serum sdLDL-C in diagnosing ACI in patients with hypertension was 0.934(95%CI:0.897-0.972).Multivariate logistic regression analysis in-dicated that SMI grade,CTA,and sdLDL-C were risk factors for ACI in hypertensive patients(P<0.01).Conclusion Combination of carotid artery plaque SMI grading,CTA,and serum sdLDL-C has high auxiliary diagnostic value for elderly hypertension patients with ACI.