Efficacy and safety of enhanced external counterpulsation in elderly patients with acute ischemic stroke complicated by coronary heart disease
10.3969/j.issn.1009-0126.2024.02.014
- VernacularTitle:增强型体外反搏治疗对老年急性缺血性脑卒中合并冠心病患者的疗效及安全性
- Author:
Lina MA
1
;
Yuqiao ZHENG
;
Yulin WANG
;
Ning XIANG
;
Jingyuan LI
;
Xuehui QIN
Author Information
1. 066000 秦皇岛市第一医院神经内科
- Keywords:
stroke;
coronary disease;
counterpulsation;
recurrence;
major adverse cardiovascular events
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(2):175-178
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the efficacy and safety of enhanced external counterpulsation(EECP)in elderly patients with acute ischemic stroke(AIS)complicated by coronary heart dis-ease(CHD).Methods A total of 65 AIS patients with CHD admitted in our hospital from Janu-ary to June 2023 were recruited and randomly divided into a control group(drug secondary pre-vention,n=32)and a treatment group(drug combined with EECP therapy,n=33).Their NIHSS score,mRS score and Canadian Cardiovascular Society(CCS)angina grade were evaluated before and after treatment and compared between the two groups.The incidences of recurrent ischemic stroke,new hemorrhagic stroke and major adverse cardiovascular events(MACE)were also recor-ded during treatment.Results The NIHSS score and mRS score were significantly decreased in both groups after treatment(P<0.01).After treatment,the NIHSS score(2.67±1.63 vs 3.56± 1.83),mRS score[1.0(0.0,1.0)vs 2.0(1.0,2.0)]and CCS grade[1.0(1.0,2.0)vs 2.0(1.0,2.0)]were obviously lower in the treatment group than the control group(P<0.05,P<0.01).There were no statistical differences in the incidence rates of recurrent ischemic stroke,new-onset hem-orrhagic stroke,and MACE between the control group and the treatment group(9.4%vs 6.1%,6.3%vs 3.0%,12.5%vs 6.1%,P>0.0 5).Conclusion EECP is a safe and effective treatment option for elderly AIS patients with CHD.