Therapeutic efficacy of automatic peritoneal dialysis on elderly patients with cardiorenal syndrome
10.3969/j.issn.1009-0126.2024.01.008
- VernacularTitle:自动腹膜透析治疗对老年心肾综合征患者的疗效
- Author:
Zhaopeng DENG
1
;
Fuzhang LUO
;
Juncai ZHOU
;
Zhijun TAN
;
Wei PAN
Author Information
1. 528200 佛山市南海区人民医院肾内科
- Keywords:
cardiorenal syndrome;
peritoneal dialysis;
kidney function tests;
heart function tests;
C-reactive protein;
tumor necrosis factor-alpha;
NT-proBNP
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(1):30-33
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the therapeutic efficacy of automatic peritoneal dialysis on elderly patients with cardiorenal syndrome(CRS).Methods A total of 260 elderly CRS patients treated at our hospital from January 2019 to January 2022 were recruited,and then randomly divided into an observation group and a control group,with 130 cases in each group.The control group received conventional basic treatment and symptomatic treatment,while the observation group received automated peritoneal dialysis treatment on this basis.Cardiac function indicators,renal function indicators,inflammatory factors,MAP and heart rate were compared between the two groups.Re-sults After treatment,significantly lower LVESD(26.29±1.19 mm vs 29.59±1.84 mm),LVEDD(47.43±1.39 mm vs 51.81±1.34 mm),LAD(30.74±1.15 mm vs 33.11±0.88 mm),and levels of NT-proBNP(1034.74±313.61 ng/L vs 2634.02±853.67 ng/L),urea(16.69±3.57 mmol/L vs 32.67±4.54 mmol/L),cystatin C(0.47±0.13 mg/L vs 0.61±0.15 mg/L),creatinine(254.74±41.15 mmol/L vs 394.09±38.61 mmol/L),TNF-α(144.14±23.16 mg/L vs 183.97± 23.37 mg/L)and hs-CRP(4.09±1.03 μg/L vs 5.45±1.17 μg/L),and higher LVEF(39.14± 4.48％vs 35.64±5.27％)were observed in the observation group than the control group(all P＜0.01).There were no significant differences in heart rate and MAP between the two groups before and after treatment(P＞0.05).Conclusion Automatic peritoneal dialysis can improve the cardiac and renal function and reduce inflammatory response in elderly CRS patients,and show positive significance for improving prognosis.
