Value of CCTA in discrimination of subtotal and chronic total occlusion of coronary artery in elderly patients
10.3969/j.issn.1009-0126.2024.01.003
- VernacularTitle:冠状动脉CT血管造影鉴别老年冠状动脉慢性完全闭塞与次全闭塞患者的价值研究
- Author:
Junli REN
1
;
Lichen REN
;
Guang YAO
;
Yonggao ZHANG
Author Information
1. 450052 郑州大学第一附属医院放射科
- Keywords:
coronary occlusion;
computed tomography angiography;
logistic models;
coronary chro-nic total occlusion;
coronary subtotal occlusion
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(1):9-12
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of coronary computed tomography angiography(CCTA)for the non-invasive discrimination of chronic total occlusion(CTO)and subtotal occlu-sion(SO).Methods A total of 134 elderly patients undergoing CCTA and invasive coronary angio-graphy in our hospital from January 2019 to December 2021 were enrolled,and assigned into CTO group(62 cases)and SO(72 cases)according to the results of the examinations.Occlusion length,shape of proximal stump(blunt/conical),and collateral vessels were measured as anatomical find-ings.Transluminal attenuation gradient was obtained by a post-processing software.Univariate and multivariate logistic regression analyses were performed to explore factors related to CTO.Re-stricted cubic splines with three knots at the 10th,50th,and 90th percentiles were used to flexibly model the association of the factors with CTO,and ROC curve was plotted to evaluate the per-formance.Results Diabetes(OR=0.423,95%CI:0.186-0.963),occlusion length(OR=1.088,95%CI:1.031-1.148)and blunt-shaped stump(OR=2.453,95%CI:1.042-5.773)were inde-pendent predictors for discriminating CTO and SO(P<0.05,P<0.01).ROC curve analysis showed that the AUC value of occlusion length in the discrimination was 0.718(95%CI:0.634-0.792,P=0.001).Conclusion CCTA can be used to discriminate CTO and SO in elderly patients.