Correlation between residual cholesterol level and vertebrobasilar artery dilatation in elderly patients with acute cerebral infarction
10.3969/j.issn.1009-0126.2023.12.022
- VernacularTitle:残余胆固醇水平与老年急性脑梗死患者椎基底动脉延长扩张症的相关性研究
- Author:
Yuqing MEI
1
;
Yanwei GUO
;
Wenting ZHANG
;
Min ZHANG
;
Guimei YANG
Author Information
1. 213000 南京医科大学附属常州市第二人民医院神经内科南京医科大学常州医学中心
- Keywords:
brain infarction;
vertebrobasilar insufficiency;
cholesterol;
logistic models
- From:Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2023;25(12):1324-1327
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between the residual cholesterol(RC)level and vertebrobasilar dilatation(VBD)in elderly patients with acute cerebral infarction(ACI).Methods A total of 325 elderly ACI patients admitted to Department of Neurology,Changzhou Second People's Hospital of Nanjing Medical University from January 2020 to July 2021 were recruited retrospectively.All of them underwent cranial MRI,CTA and biochemical test for plasma levels of TC,TG,LDL-C and HDL-C and other biochemical indicators.According to the imaging diagnostic criteria,they were divided into VBD group(52 cases)and non-VBD group(273 cases).Their clini-cal data were compared between the two groups,and the relationship between RC level and VBD was analyzed in the elderly ACI patients.Results Significant differences were observed in age,sex,hypertension,history of smoking and TC and RC levels between the VBD group and non-VBD group(P＜0.05,P＜0.01).Multivariate logistic regression analysis showed that after adjus-ting the potential confounding factors,age(OR=1.126,95％CI:1.065-1.191,P=0.000),male(OR=4.163,95％CI:11.173-10.120,P=0.002),and RC level(OR=1.270,95％CI:1.151-1.401,P=0.000)were independent risk factors for VBD in elderly ACI patients.Conclusion Age,male and RC level are independent risk factors for VBD in elderly ACI patients.High RC lev-el may increase the risk of VBD.
