Impact of intravascular embolization therapy at different times on prognosis of elderly patients with IA rupture and bleeding
10.3969/j.issn.1009-0126.2023.12.020
- VernacularTitle:不同时机行血管内介入栓塞治疗对老年颅内动脉瘤破裂出血患者预后的影响
- Author:
Huaming CHEN
1
;
Zhixing XU
;
Jin WU
Author Information
1. 665000 普洱市人民医院神经外科
- Keywords:
intracranial aneurysm;
prognosis;
hemorrhage;
intracranial aneurysm rupture
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2023;25(12):1315-1318
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the impact of different times for endovascular embolization thera-py on the prognosis of elderly patients with intracranial aneurysm(IA)rupture and bleeding.Methods Clinical data of 156 elderly patients with IA rupture and bleeding admitted to our hos-pital from January 2019 to December 2022 were collected and analyzed retrospectively.All of them underwent intravascular embolization treatment.According to the timing of intravascular emboli-zation,they were divided into super early group(within 24 h from onset,n=66)and delayed group(in 24 h after onset,n=90).The Hunt-Hess grade,aneurysm location,cerebrospinal fluid exchange,embolization situation and success rate of embolization treatment were observed and re-corded.The prognosis of the two groups were evaluated with NIHSS score and mRS score.Results In terms of prognosis,no significant differences were observed in cerebrovascular spasm,disorders of consciousness,limb movement disorder,proportion of re-bleeding,and mRS score between the two groups(P>0.05).The ratio of hydrocephalus was obviously lower in the super early group than the delayed group(4.55%vs 15.56%,P<0.05).Though no statistical difference was seen in the pre-operative NIHSS score between the two groups(P>0.05),the score was declined after treatment(P<0.05),with that of the super early group notably lower than that in the delayed group(6.62±1.25 vs 7.82±1.35,P<0.01).Conclusion Super early endovascular embolization can effectively reduce the incidence of hydrocephalus and improve neurological function in elderly patients with IA rupture and bleeding.