Prognostic value of myocardial contraction fraction by cardiac magnetic resonance for elderly patients with cardiac amyloidosis
10.3969/j.issn.1009-0126.2023.12.005
- VernacularTitle:心脏磁共振心肌收缩分数评估老年心肌淀粉样变性患者预后的价值
- Author:
Wei DENG
1
;
Huimin XU
;
Yangcheng XUE
;
Hongmin SHU
;
Weishu HOU
;
Min LIU
;
Jingwei SHU
;
Yongqiang YU
;
Ren ZHAO
;
Xiaohu LI
Author Information
1. 230022 合肥,安徽医科大学第一附属医院医学影像科
- Keywords:
amyloidosis;
prognosis;
cardiac magnetic resonance;
myocardial contraction fraction
- From:Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2023;25(12):1251-1254
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the prognostic value of MCF in elderly patients with cardiac amy-loidosis using CMR.Methods A retrospective analysis was conducted on 54 elderly patients with cardiac amyloidosis diagnosed in our hospital.All patients underwent CMR imaging.They were di-vided into a survival group of 25 cases and a mortality group of 29 cases based on clinical out-comes.Correlations of MCF with CMR parameters and biochemical indicators were evaluated.Cox regression analysis was performed to identify independent predictors of patient survival.Survival analysis was used to assess the value of MCF in predicting patient prognosis.Results The surviv-al group had significantly higher MCF than the mortality group[(70.63±24.72)％vs(43.59± 13.36)％,P=0.001].As MCF increasing,LVEF level was in an increasing trend,while LVMI,LVGPWT,ECV,and troponin T and NT-proBNP levels showed a decreasing trend.Multivariate Cox regression analysis revealed that MCF was an independent predictor of patient survival(HR=0.922,95％CI:0.866-0.981,P=0.011).Kaplan-Meier survival curve showed that the patients with MCF＞57％had significantly higher survival rates than those with MCF ≤57％(P＜0.01).Conclusion MCF is an effective imaging indicator for evaluating the prognosis of elderly patients with cardiac amyloidosis,which can help identify high-risk patients and guide clinical treatment.
