Association between visceral fat area measured with quantitative CT and fatty liver in normal weight population
10.3760/cma.j.cn115624-20231102-00267
- VernacularTitle:正常体重人群中基于定量CT技术测量内脏脂肪面积与脂肪肝的相关性
- Author:
Qi QIAO
1
;
Yang ZHOU
;
Yongbing SUN
;
Xin QI
;
Yawei DU
;
Zhonglin LI
;
Zhi ZOU
;
Xiaoling WU
;
Jing ZHOU
;
Gong ZHANG
;
Min QU
;
Xiaolin ZHANG
;
Yong WANG
;
Shewei DOU
;
Hongming LIU
;
Fengshan YAN
;
Jiadong ZHU
;
Yongli LI
Author Information
1. 郑州大学人民医院 河南省人民医院医学影像科，郑州 450003
- Keywords:
Body mass index;
Obesity;
Fatty liver;
Blood biochemical index;
Correlation analysis;
Quantitative CT
- From:
Chinese Journal of Health Management
2024;18(2):120-126
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the association between visceral fat area (VFA) and fatty liver based on quantitative CT (QCT) in people receiving health examination with normal body mass index (BMI).Methods:A cross-sectional study. A total of 1 305 physical examiners who underwent chest CT and QCT examination in the Department of Health Management of Henan Provincial People′s Hospital from January to December 2021 were retrospectively selected as subjects. The physical components at the central level of the lumbar two cone were measured with QCT, including subcutaneous fat area (SFA), VFA and liver fat content (LFC). And the metabolic indexes, such as blood lipids and blood glucose, were collected. The t-test and χ2 test were used to analyze the correlation between the detection rate of fatty live and LFCr and age and gender. According to level of VFA (<100 cm 2, 100-150 cm 2 and≥150 cm 2), the subjects were divided into three groups, and one-way ANOVA and χ2 test were used in comparison between groups. Multiple linear regression was used to analyze the correlation between VFA and metabolic indexes and LFC. Results:Of the 1 305 subjects, there were 634 males and 671 females. The detection rate of fatty liver in normal BMI population was 65.67%, and it was 72.71% and 59.02% respectively in men and women ( χ2=27.12, P<0.001), and the detection rate of fatty liver and LFC increased with age (both P<0.05). With the increase of VFA, the age, BMI, SFA, LFC, total cholesterol (TC), triacylglycerol (TG), low-density lipoprotein cholesterol (LDL-C), fasting blood glucose (FBG), alanine aminotransferase (ALT), blood uric acid and prevalence of fatty liver increased (all P<0.05), and the low-density lipoprotein cholesterol (HDL-C) decreased ( P<0.001). Multiple linear regression analysis showed that after adjustment for age factors, regardless of male or female, LFC was independently positively related with VFA, BMI, and ALT (male β=0.206, 0.145, 0.174, female β=0.194, 0.150, 0.184; all P<0.05). FBG was positively correlated with male independently ( β=0.134; P<0.001). The indicators related to female independently were TC, TG, and blood uric acid ( β=-0.121, 0.145, 0.141, all P<0.05) Conclusion:In the population receiving health examination with normal BMI, the VFA measured by QCT technique is closely related to fatty liver.
