Clinical application of PET automatic drug infusion system combined with power peripherally inserted central catheter in 18F-FDG PET/CT imaging
10.3760/cma.j.cn321828-20230524-00148
- VernacularTitle:PET自动给药系统联合耐高压经外周静脉置入中心静脉导管在 18F-FDG显像中的临床应用
- Author:
Qinli QI
1
;
Lingzhou ZHAO
;
Donghui CHEN
;
Xingmei ZHOU
;
Changcun LIU
;
Shan WU
;
Ying ZHANG
;
Jinhua ZHAO
Author Information
1. 上海交通大学医学院附属第一人民医院核医学科，上海 200080
- Keywords:
Infusion pumps;
Central venous catheters;
Injection, intravenous;
Fluorodeoxyglucose F18;
Positron-emission tomography;
Tomography, X-ray computed
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2023;43(11):684-688
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the feasibility of PET automatic drug infusion system combined with power peripherally inserted central catheter (PICC) for 18F-FDG injection and PET/CT imaging. Methods:Fifty patients with malignant neoplasms who underwent 18F-FDG PET/CT imaging in Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine between December 2021 to July 2022 were prospectively enrolled. They were equally divided into power PICC group and peripheral venipuncture group. PET automatic drug infusion system was respectively connected with the pre-established channels of power PICC and peripheral venipuncture for 18F-FDG injection. Each patient underwent a routine PET/CT imaging at 1 h post-injection. The blood glucose, body weight, prescription dose and injection dose were recorded, and SUV max in the liver and cavoatrial junction were measured in both groups. The independent-sample t test was performed to compare the differences between 2 groups. The power PICC tip positions after 18F-FDG injection in power PICC group were observed. Results:The liver SUV max in the power PICC group and peripheral group were 2.54±0.50 and 2.57±0.31 ( t=0.37, P=0.716), and the SUV max of cavoatrial junction in the 2 groups were 1.68±0.25 and 1.63±0.22 ( t=-0.78, P=0.441), respectively. No significant differences were found in blood glucose, body weight, prescription dose and injection dose between the 2 groups ( t values: 0.00-0.13, all P>0.05). The ratios of injection dose to prescription dose in the 2 groups were 0.998 3±0.007 3 and 0.997 6±0.016 5, respectively, indicating high injection accuracy of the injection methods. No obvious drug residue was displayed at the end of catheter, resulting in good imaging quality. All the tip positions after injection were between T5 and T8, in line with the standardization management of power PICC. Conclusion:PET automatic drug infusion system combined with power PICC can be safely used for 18F-FDG injection and PET/CT imaging with less injection puncture.
