Application of indocyanine green fluorescence imaging in laparoscopic surgery for pancreatic cancer
10.3760/cma.j.cn113884-20230712-00002
- VernacularTitle:吲哚菁绿荧光成像在腹腔镜胰腺癌手术中的应用分析
- Author:
Shihang XI
1
;
Xiaoming WANG
;
Guannan WANG
;
Yaqi JIANG
;
Daohai QIAN
;
Xiaosan FANG
Author Information
1. 皖南医学院第一附属医院肝胆外科，芜湖 241001
- Keywords:
Pancreatic neoplasms;
Indocyanine green;
Fluorescence imaging
- From:
Chinese Journal of Hepatobiliary Surgery
2024;30(3):193-196
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the application of indocyanine green (ICG) fluorescence imaging in laparoscopic resection of pancreatic cancer.Methods:Data of 15 patients undergoing laparoscopic surgery for pancreatic cancer in the Department of Hepatobiliary Surgery of the First Affiliated Hospital of Wannan Medical College from June 2022 to March 2023 were retrospectively analyzed, including 13 males and 2 females, aged (67.0±8.6) years. ICG were intraoperatively injected to visualize the lesion and guide surgical resection. The surgical methods, postoperative pathology, ICG fluorescence imaging and tumor margins were reviewd.Results:Among the patients, seven underwent laparoscopic pancreaticoduodenectomy, seven underwent laparoscopic radical antegrade modular pancreaticosplenectomy, and one conversed to open pancreaticoduodenectomy due to combined superior mesenteric vein reconstruction. Postoperative pathology confirmed pancreatic moderately differentiated adenocarcinoma in nine cases, pancreatic moderately-low differentiated adenocarcinoma in four cases, pancreatic follicular cell carcinoma in one case, and inflammatory lesion in one case. Negative surgical margins were confirmed in all cases. Pancreatic lesion were visualized in 14 cases (fluorescent delineation of the tumor capsule) but not well visualized in one case (with moderately differentiated adenocarcinoma). In the case of inflammatory disease, the lesion parenchyma were visualized.Conclusion:ICG injection in laparoscopic surgery enables visualization of pancreatic tumor, which facilitates tumor localization and margin determination.
