Differential diagnostic value of fluoroscopy-guided percutaneous transhepatic forceps biopsy for biliary strictures: a meta-analysis
10.3760/cma.j.cn113884-20221121-00432
- VernacularTitle:透视引导下经皮经肝胆管内钳夹活检对胆管狭窄鉴别诊断价值的荟萃分析
- Author:
Mengyao SONG
1
;
Xueliang ZHOU
;
Dechao JIAO
Author Information
1. 郑州大学第一附属医院介入科，郑州 450052
- Keywords:
Bile ducts;
Forceps biopsy;
Meta-analysis;
Diagnosis
- From:
Chinese Journal of Hepatobiliary Surgery
2023;29(10):768-775
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the fluoroscopy-guided percutaneous transhepatic forceps biopsy (PTFB) in the diagnosis of biliary strictures.Methods:Literatures on diagnosis of biliary strictures by PTFB published from January 2001 to August 2022 were obtained by searching the databases of PubMed, Embase, Web of Science, the Cochrane Library, China National Knowledge Infrastructure (CKNI), Wanfang, VIP, and China Biology Medicine disc (CBM). Literature inclusion and exclusion criteria were established and the retrieved literature was screened. The quality of the included literature was evaluated using the quality assessment of diagnostic accuracy studies (QUADAS-2). Statistical analysis was performed by using Meta-disc software and Stata software.Results:Eighteen articles involving 1 935 patients were finally included. The heterogeneity test suggested no threshold effect, but there was non-threshold heterogeneity in sensitivity and negative likelihood ratio due to other reasons, so a random-effects model was used, and a fixed-effects model were used for the remaining outcome indexes used due to low heterogeneity. The results showed that the pooled sensitivity of fluoroscopy-guided PTFB for the diagnosis of biliary strictures was 0.796 (95% CI: 0.776-0.814), the pooled specificity was 1.000 (95% CI: 0.985-1.000), the pooled positive likelihood ratio was 21.532 (95% CI: 11.281-41.098), the pooled negative likelihood ratio was 0.234(95% CI: 0.169-0.323), the pooled diagnostic odds ratio was 94.321(95% CI: 46.744-190.320), and the area under the summary receiver operating characteristic curve was 0.929. The pooled complication rate was 9.2% (95% CI: 6.4%-12.0%). Conclusion:Fluoroscopy-guided PTFB may be a superior diagnostic tool for biliary strictures.
