Effect of Lovastatin on Serum Lipids in Primary Hypercholesterolemia.
10.4070/kcj.1991.21.2.322
- Author:
Wee Hyun PARK
;
Shin Woo KIM
;
Eon Jo WOO
;
Seung Wan KANG
;
Jin Yong HWANG
;
Shung Chull CHAE
;
Jae Eun JUN
- Publication Type:Original Article
- Keywords:
Lovastatin;
Hypercholesterolemia
- MeSH:
Cholesterol, HDL;
Cholesterol, LDL;
Humans;
Hypercholesterolemia*;
Lovastatin*;
Triglycerides
- From:Korean Circulation Journal
1991;21(2):322-327
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
10 Patients with primary hypercholesterolemia were treated for 12 weeks with lovastation(20mg t.i.d). Lovastatin reduced mean total and low density lipoprotein cholesterol by 43% and 57% respectively(p<0.001). High density lipoprotein cholesterol and triglyceride levels were unchanged by the drug. Adverse effects attributable to lovastatin were not observed. Thus lovastatin is considered as an effective lipid lowering agent for the treatment of primary moderate hypercholesterolemia.